8.2.2 A High Spatial Resolution MEA for Voltammetric Analysis of Trace Metals in Water Pollution Based on Partial Least Squares Regression
- Event
- 14th International Meeting on Chemical Sensors - IMCS 2012
2012-05-20 - 2012-05-23
Nürnberg/Nuremberg, Germany - Chapter
- 8.2 Electrochemical Sensors II
- Author(s)
- H. Zhao, W. Cai, H. Wan, D. Ha, P. Wang - Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University (China)
- Pages
- 679 - 682
- DOI
- 10.5162/IMCS2012/8.2.2
- ISBN
- 978-3-9813484-2-2
- Price
- free
Abstract
Estimation of heavy metals in water has been paid significant attention because of the toxicity of such metals on the whole ecological system. A microelectrode array (MEA) of individually addressable microelectrodes was fabricated for cadmium, lead and copper analysis in water pollution. The ratio of interelectrode distance to the electrode diameter of the MEA was sufficient enough to get a collective current response while maintaining the excellent features of single microelectrodes. Cyclic voltammograms made in various scan rates confirmed that a high spatial resolution MEA was constructed with no diffusion layers overlapping. Then the mercury film Au-MEA was utilized to detect cadmium, lead and copper ions using differential pulse anodic stripping voltammetry (DPASV). The sensitivity of 130nA/microgramm, 52nA/microgramm and 46nA/microgramm for Cd2+, Pb2+ and Cu2+ ions, separately, were achieved using this microsensing chip. Calibrations were made via partial least-squares regression (PLSR) modeling. Well correlation was found between the lab-determined values and the values predicted from PLSR calibration.