C4.4 - Ultrasonic Dispersion of Particles in Lab-on-Chip Systems for Enzyme-Linked-Immunoassays
- Event
- AMA Conferences 2015
2015-05-19 - 2015-05-21
Nürnberg, Germany - Band
- Proceedings SENSOR 2015
- Chapter
- C4 - Medical Sensors
- Author(s)
- L. Brandhoff, M. Vellekoop - University of Bremen (Germany), H. Zirath, J. Peham, H. Wiesinger-Mayr - Austrian Institute of Technology, Vienna (Austria), C. Redl - Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna (Austria), A. Spittler - Medical University of Vienna (Austria), A. Haller - Vienna University of Technology Austria), G. Schnetz - Biegler GmbH, Mauerbach (Austria)
- Pages
- 418 - 421
- DOI
- 10.5162/sensor2015/C4.4
- ISBN
- 978-3-9813484-8-4
- Price
- free
Abstract
We present a system for dispersing colloids on-chip via ultrasound. Superparamagnetic beads used in
Enzyme-Linked-Immunosorbent-Assays (ELISAs) can be efficiently dispersed in the on-chip reaction chamber by this method. By keeping the ultrasonic transducer off-chip and focusing the ultrasound through a horn towards the reaction chamber, a low-cost disposable chip design can be used instead of highly complicated and expensive integrated systems. This is advantageous especially in biological and medical applications where single-use devices are needed to prevent cross contamination between samples.