4.2.6 Comparison of LabelFree ACh Image Sensors Based on CCD and LAPS
- Event
- 14th International Meeting on Chemical Sensors - IMCS 2012
2012-05-20 - 2012-05-23
Nürnberg/Nuremberg, Germany - Chapter
- 4.2 Biosensors IV (Systems)
- Author(s)
- S. Takenaga, K. Sawada - Toyohashi University of Technology (Japan), C. Werner, M. Schöning - Institute of Nano- and Biotechnologies (INB), FH Aachen, Campus Jülich (Germany)
- Pages
- 356 - 359
- DOI
- 10.5162/IMCS2012/4.2.6
- ISBN
- 978-3-9813484-2-2
- Price
- free
Abstract
Semiconductor-based chemical image sensors, like the pH-image sensor based on a charge-coupled device (CCD) or the light-addressable potentiometric sensor (LAPS), are becoming a powerful tool for label-free imaging of biological phenomena. We have proposed a polyion-based enzymatic membrane to develop an acetylcholine (ACh)-image sensor for neural cell activity observations. In this study, a CCD-type ACh image sensor and a LAPStype ACh image sensor were fabricated and the prospect of both sensors was clarified by making a comparison of their basic characteristics.