P1 - Induced cellular deformation as a standardized measurement method based on modified Micro-ESPI
- Event
- AMA Conferences 2013
2013-05-14 - 2013-05-16
Nürnberg - Band
- Proceedings OPTO 2013
- Chapter
- OP - Poster Session
- Author(s)
- C. Stollfuß, K. Lietzau, A. Foitzik - Technical University of Applied Sciences Wildau (Germany)
- Pages
- 85 - 89
- DOI
- 10.5162/opto2013/oP.1
- ISBN
- 978-3-9813484-3-9
- Price
- free
Abstract
During the course of their lifetime cells are exposed to different kinds of mechanical stress. These mechanical effects have a strong influence on a single cell, aggregated cells, their structure and metabolism especially in case of immunologic reaction similar to a chemical stimuli.Aim of this work is to introduce a modified electronic speckle pattern interferometry (ESPI) setup to this field of science to validate induced deformations in certain biological samples contact-free and thus close to their natural conditions.In the long term it is the aim to develop a “set” of these reference values and to use them in term of preliminary analysis for medical treatment.In conclusion this could lead to complete new approach in cell based analysis.