B2.1 - Micro-and Nanosensors for Biological Applications
- Event
- SENSOR+TEST Conferences 2009
2009-05-26 - 2009-05-28
Congress Center Nürnberg - Band
- Proceedings SENSOR 2009, Volume I
- Chapter
- B2 - Medical Application II
- Author(s)
- G. Urban - Universität Freiburg, Freiburg, Germany
- Pages
- 163 - 167
- DOI
- 10.5162/sensor09/v1/b2.1
- ISBN
- 978-3-9810993-4-8
- Price
- free
Abstract
Recent progress in Microsystems technologies for creating small, integrated and reliable microelectronic devices in combination with biological sensing elements has raised the expectation to get a comprehensive insight into dynamic cellular metabolic events and subsequently a complete understanding of the metabolism of human biology. Such micro- and nanobiosensor in combination with appropriate micro fluidics enable the simultaneous description and moreover monitoring of gene, protein expression and metabolic states in a biosystem. This knowledge will undoubtedly lead to new future pharmaceutical therapies. There are a lot of challenging problems to be overcome to reach this goal: Microsystems monitoring of physical parameters in biological systems are well established whereas chemo and biosensors are available for only a few parameters and mainly as in vitro devices. Gene-arrays entered the research market but are up to now not clinical practice and protein arrays are in a developmental state with promising results however far from a mature reproducible state. For getting insights into metabolic events intra- and extracellularly some new and promising technologies are under research and will undoubtedly revolutionize system biology.