P1.5.4 Characterization of Biodegradable Polymers with Capacitive Field-effect Sensors
- Event
- 14th International Meeting on Chemical Sensors - IMCS 2012
2012-05-20 - 2012-05-23
Nürnberg/Nuremberg, Germany - Chapter
- P1.5 FET-based Sensors
- Author(s)
- S. Schusser, A. Poghossian, M. Leinhos, M. Schöning - Institute of Nano- and Biotechnologies (INB), FH Aachen (Germany) and Peter Grünberg Institute (PGI-8), Research Centre Jülich GmbH (Germany), P. Wagner - Institute for Materials Research, Hasselt University (Belgium)
- Pages
- 1035 - 1037
- DOI
- 10.5162/IMCS2012/P1.5.4
- ISBN
- 978-3-9813484-2-2
- Price
- free
Abstract
A field-effect capacitive sensor has been applied for the real-time in-situ monitoring of degradation of biopolymers for the first time. The sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of polymers induced by degradation processes. The feasibility of this approach has been experimentally proven by using the commercially available biomedical polymer poly(D,L-lactic acid) as a model system. The degradation of the poly(D,L-lactic acid) was accelerated by changing the degradation medium from neutral (pH 7.2) to alkaline (pH 9) condition, resulting in drastic changes in the capacitance of a polymer-modified field-effect sensor.