2025 SMSI Bannerklein

P2BM.4 - Selective Trapping of Bacteria with Molecularly Imprinting Film under External Field

Event
17th International Meeting on Chemical Sensors - IMCS 2018
2018-07-15 - 2018-07-19
Vienna, Austria
Chapter
P-2 - Biomimetic Sensors
Author(s)
S. Tokonami, E. Shimizu - Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University, Osaka (Japan), M. Tamura, T. Iida - Research Institute for Light-induced Acceleration System (RILACS), Osaka (Japan)
Pages
692 - 693
DOI
10.5162/IMCS2018/P2BM.4
ISBN
978-3-9816876-9-9
Price
free

Abstract

The mechanism of selective trapping of macroscopic bacteria by the cavities on the surface of the bacterial imprinted film from was unsolved. Here, we discuss the physicochemical mechanism of rapid specific identification of bacteria using an alternating electric field and a quartz crystal microbalance. We have experimentally revealed that the selectivity strongly depends on the specific binding of surface chemical structure (SCS) and molecular recognition site (MRS) under the various conditions of SCS on bacteria damaged by UV light, heat and antibacterial drugs. We also performed the theoretical analysis based on the "self-consistent electromagnetic theory taking into account the MRS, and well explained the experimentally observed selectivity from the nanoscale physicochemical viewpoint.

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