8.2 - KUNSTBLUT - Artificial Blood for Experimental Flow Visualization in Intracranial Aneurysms
- Event
- iCCC2024 - iCampµs Cottbus Conference
2024-05-14 - 2024-05-16
Cottbus - Band
- Vorträge
- Chapter
- Material-& Prozesstechnologien
- Author(s)
- C. Winkler, G. Hentschel, M. Müller, B. Glasmacher - Leibniz Universität Hannover, Garbsen , P. Berg - Otto-von-Guericke-Universität Magdeburg, Magdeburg, K. Zähringer - Otto-von-Guericke-Universität Magdeburg, Magdeburg, F. Rummel - NETZSCH-Gerätebau GmbH, Selb
- Pages
- 108 - 111
- DOI
- 10.5162/iCCC2024/8.2
- ISBN
- 978-3-910600-00-3
- Price
- free
Abstract
Multiphase blood substitute fluids are currently under development for quantifying (pathological) he-modynamics in intracranial aneurysms using particle image velocimetry (PIV). The challenge lies in replicating the thin elastic 7.5 μm red blood cells (erythrocytes). These were reproduced by hydrogel beads. Various blood substitute fluids could be successfully produced, including artificial plasma from a glycerol-water mixture, mixed with spherical and disc-shaped agarose erythrocytes and disc-shaped NOA60 erythrocytes. Artificial erythrocytes, so far up to 29 μm in diameter, were synthesized using microfluidic methods. PIV seeding particles were integrated into the beads to make them visible with optical measurement systems such as PIV and particle tracking velocimetry (PTV).