F10 - Nanoflower-based SERS active particles for chemosensing
- Event
- 11. Dresdner Sensor-Symposium 2013
2013-12-09 - 2013-12-11
Dreikönigskirche - Haus der Kirche Dresden - Chapter
- 6. Neuartige Sensormaterialien und –technologien
- Author(s)
- D. Cialla, K. Weber, J. Popp, S. Pahlow, A. März - Friedrich-Schiller University Jena/D
- Pages
- 345 - 350
- DOI
- 10.5162/11dss2013/F10
- ISBN
- 978-3-9813484-5-3
- Price
- free
Abstract
A new facile method for the modification of magnetic beads with a SERS active substrate is introduced. The technique involves enzymatically induced silver deposition. Horse radish peroxidase is immobilized on streptavidin modified beads using a short biotinylated oligonucleotide as linker molecule. The enzyme induces the reduction of the silver ions to elementary silver, resulting in the growth of flower-like silver nanoparticles on the surface of the magnetic beads. Due to the unique
structure of the silver nanoflowers they provide an enhancement of the inherently weak Raman signal of analyte molecules. In this study the structure of the silver modified magnetic beads and their SERS properties are investigated using adenine as model analyte.