P1.1.5 A Real-Time Heparin Sensor Using A Gate Effect of Molecularly Imprinted Polymer
- Event
- 14th International Meeting on Chemical Sensors - IMCS 2012
2012-05-20 - 2012-05-23
Nürnberg/Nuremberg, Germany - Chapter
- P1.1 Biosensors
- Author(s)
- Y. Yoshimi, M. Ohshima, K. Sato - Department of Applied Chemistry, Shibaura Institute of Technology (Japan)
- Pages
- 830 - 831
- DOI
- 10.5162/IMCS2012/P1.1.5
- ISBN
- 978-3-9813484-2-2
- Price
- free
Abstract
The topic of this work is development of a sensor for monitoring heparin level by using gate effect of molecularly imprinted polymer (MIP). Cationic monomer and crosslinking monomer was graftcopolymerized onto an electrode in the presence of heparin as a template. The faradic current at the grafted electrode was sensitive to heparin concentration. The response time to stepwise change in heparin concentration was no more than 15 s. Then the heparin-imprinted polymer is promising for real-time heparin sensor, which will improve the safety of extracorporeal therapy.