OT6.7 - Hydrogel-based Sensing Technology for Quantitative Measurements of Low Concentrations of Proteins in the Presence of Interferents
- Event
- EUROSENSORS XXXVI
2024-09-01 - 2024-09-04
Debrecen (Hungary) - Band
- Lectures
- Chapter
- OT6 - Biochemical sensors, Microfluidics, Lab-on-a-Chip and Organ-On-Chip Systems
- Author(s)
- R. Gupta, K. Haliru - University of Birmingham, Birmingham (United Kingdom)
- Pages
- 151 - 152
- DOI
- 10.5162/EUROSENSORSXXXVI/OT6.7
- ISBN
- 978-3-910600-03-4
- Price
- free
Abstract
We report a hydrogel-based sensing technology for the measurement of proteins with a limit of detection of 0.003 ppm or 53 pM for an exemplar analyte, streptavidin, while being less laborious than the state-of-the-art method, enzyme-linked immunosorbent assay. Equally, we showed that the presence of high molecular weight interferents such as mucin at 100- and 1000-times higher concentrations than the exemplar analyte did not influence protein measurement.