OT6.111 - Development of an ISFET-based system for genetic detection of leukemia oncogene
- Event
- EUROSENSORS XXXVI
2024-09-01 - 2024-09-04
Debrecen (Hungary) - Band
- Lectures
- Chapter
- OT6 - Biochemical sensors, Microfluidics, Lab-on-a-Chip and Organ-On-Chip Systems
- Author(s)
- L. S. Oliveira, C. A. S. Andrade, M. D. L. Oliveira - Federal University of Pernambuco, Recife (Brazil), N. Lucena-Silva - Oswaldo Cruz Foundation, Recife (Brazil)
- Pages
- 165 - 166
- DOI
- 10.5162/EUROSENSORSXXXVI/OT6.111
- ISBN
- 978-3-910600-03-4
- Price
- free
Abstract
A Point-of-care device was developed using Ion-selective field-effect transistors (ISFETs) for real-time detection of molecular targets, eliminating the requirement for a highly controlled environment. This device successfully detected the translocation between chromosomes 12 and 21 (t(12;21)), which is one of the most common mutations associated with childhood acute lymphoblastic leukemia (ALL).