OT6.195 - Aptamer-based Electrochemical Sensor for the Monitoring of Carbamazepine in Freshwater Systems
- Event
- EUROSENSORS XXXVI
2024-09-01 - 2024-09-04
Debrecen (Hungary) - Band
- Lectures
- Chapter
- OT6 - Biochemical sensors, Microfluidics, Lab-on-a-Chip and Organ-On-Chip Systems
- Author(s)
- P. Clément, A. Finelli, X. Lefèvre, S. Khan, A. Beard, R. Pugin - Centre Suisse d’Electronique et de Microtechnique, Neuchâtel (Switzerland)
- Pages
- 177 - 178
- DOI
- 10.5162/EUROSENSORSXXXVI/OT6.195
- ISBN
- 978-3-910600-03-4
- Price
- free
Abstract
Carbamazepine (CBZ) is an active compound in commonly used drug and is highly durable in the environment, particularly in wastewater, which raises concerns about potential risks to animals and humans. We present an aptamer-based electrochemical sensor labelled with a redox probe which conformational change upon binding event is recorded by square-waved voltammetry. The electro-chemical sensor operated in concentrations range from 2.5 pM to 250 μM in buffer. This technology provides a potential method to enable the monitoring of CBZ in treated water.