OT6.228 - Simple Microfluidic System for Point-of-Care Therapeutic Drug Monitoring of Anticancer Drugs
- Event
- EUROSENSORS XXXVI
2024-09-01 - 2024-09-04
Debrecen (Hungary) - Band
- Lectures
- Chapter
- OT6 - Biochemical sensors, Microfluidics, Lab-on-a-Chip and Organ-On-Chip Systems
- Author(s)
- A. Füredi, D. Bereczki, P. Fürjes - HUN-REN Centre for Energy Research, Budapest (Hungary)
- Pages
- 185 - 186
- DOI
- 10.5162/EUROSENSORSXXXVI/OT6.228
- ISBN
- 978-3-910600-03-4
- Price
- free
Abstract
Therapeutic Drug Monitoring (TDM) would be a game changer for cancer therapy, however due to the current methods applied to follow the drug concentrations in the blood are expensive and require spe-cialized expertise and instruments. Point-of-Care (PoC) TDM system has never realized. Here we pre-sent a fluorescence-based PoC microfluidic solution to monitor blood levels of anticancer agents. Using blood samples from mouse models of malignancies and veterinary cancer patients we prove our ap-proach to be suitable for TDM in an experimental environment and have the potential to ultimately per-sonalize chemotherapy.