OT6.137 - Insights into Graphene-Based Sensors for VOC biomarkers of lung cancer: A DFT Perspective
- Event
- EUROSENSORS XXXVI
2024-09-01 - 2024-09-04
Debrecen (Hungary) - Band
- Lectures
- Chapter
- OT6 - Biochemical sensors, Microfluidics, Lab-on-a-Chip and Organ-On-Chip Systems
- Author(s)
- I. Shtepliuk, J. Eriksson, D. Puglisi - Linköping University, Linköping (Sweden)
- Pages
- 171 - 172
- DOI
- 10.5162/EUROSENSORSXXXVI/OT6.137
- ISBN
- 978-3-910600-03-4
- Price
- free
Abstract
In this work, we address key scientific questions regarding the use of graphene for lung cancer bi-omarker detection. The volatile organic compound (VOC) biomarkers of lung cancer were classified into nonpolar, polar with small dipole moments, and polar with large dipole moments. Using density functional theory (DFT) calculations, we examine the adsorption capacities of various VOC biomarkers on graphene surface. The analysis of binding energies provides valuable insights for designing sensi-tive and selective sensors for detecting lung cancer VOC biomarkers using graphene, potentially ad-vancing early diagnosis and treatment of this disease.