PT6.58 - Peptide-based biosensor for real-time monitoring of protease biomarkers
- Event
- EUROSENSORS XXXVI
2024-09-01 - 2024-09-04
Debrecen (Hungary) - Band
- Poster
- Chapter
- PT6 - Biochemical sensors, Microfluidics, Lab-on-a-Chip and Organ-On-Chip Systems
- Author(s)
- P. Rai, A. Tarasov - Kaiserslautern University of Applied Sciences (IMST), Zweibrücken (Germany)
- Pages
- 427 - 428
- DOI
- 10.5162/EUROSENSORSXXXVI/PT6.58
- ISBN
- 978-3-910600-03-4
- Price
- free
Abstract
Here we propose a peptide-based assay using a specific combination of linker and peptides to design a robust biosensor for proteases. The implementation of a cleavage-based mechanism results in the sensitive and specific detection of a clinically relevant biomarker (MMP-9). The developed assay is characterized using real-time electrical and optical techniques and demonstrates its potential as a tool for the detection of MMP-9.