PT6.284 - Evaluation of Cell Plating Efficiency on Polymer Surfaces for Organ-on-a-Chip Applications
- Event
- EUROSENSORS XXXVI
2024-09-01 - 2024-09-04
Debrecen (Hungary) - Band
- Poster
- Chapter
- PT6 - Biochemical sensors, Microfluidics, Lab-on-a-Chip and Organ-On-Chip Systems
- Author(s)
- G. Zal, A. N. Seyitoglu, R. Bajwa, O. Kutlu, M. K. Yapici - Sabanci University, Istanbul (Turkey)
- Pages
- 473 - 474
- DOI
- 10.5162/EUROSENSORSXXXVI/PT6.284
- ISBN
- 978-3-910600-03-4
- Price
- free
Abstract
Due to their many benefits, polymers have gained popularity recently, particularly in the biomedical industry. SU-8 and polydimethylsiloxane (PDMS) in particular have drawn notice for their advanta-geous qualities, such as chemical stability and biocompatibility. Proper cellular function in biological environments depends on effective cell-surface interactions. A new method of surface modification that involves coating Poly-L-lysine (PLL) and applying oxygen plasma treatment appears to be promis-ing in improving the adhesion of HEK 293 cells to PDMS and SU-8 surfaces.