OT6.165 - Nanosensor for GHB detection in urine samples
- Event
- EUROSENSORS XXXVI
2024-09-01 - 2024-09-04
Debrecen (Hungary) - Band
- Lectures
- Chapter
- OT6 - Biochemical sensors, Microfluidics, Lab-on-a-Chip and Organ-On-Chip Systems
- Author(s)
- E. Garrido, A. Valero-Martínez, R. Martínez-Máñez - Universitat de València, València (Spain)
- Pages
- 175 - 176
- DOI
- 10.5162/EUROSENSORSXXXVI/OT6.165
- ISBN
- 978-3-910600-03-4
- Price
- free
Abstract
In the present project, we report the design, synthesis, and evaluation of a nanosensor based on mesoporous silica nanoparticles (MSNs) loaded with a fluorescent dye and functionalized with the GABA B receptor for GHB detection in urine samples. GABA B receptor acts as a molecular gate due to its interaction with the agonist, baclofen. Subsequently, the nanodevice will be integrated into a lateral flow assay coupled with a smartphone capable of measuring the fluorescent signal produced by the released dye.